Functional Renal Imaging: Where Physiology, Nephrology, Radiology and Physics Meet

Dear colleagues and friends,

this symposium is designed to bring together scientists and clinicians from several disciplines, in a unique attempt to shape the future of renal functional imaging. It will provide an overview of cutting edge clinical and pre-clinical renal imaging techniques, and explore the clinical relevance of renal imaging, the future directions of renal functional MR, and the harmonization of these approaches with clinical applications.

We aim to provide a platform for fruitful engagement with colleagues and peers, and to foster the development of local, national and international collaborations to explore multi-disciplinary imaging approaches. The symposium is tailored to attract basic scientists, clinical scientists and clinicians from physiology, nephrology, radiology, internal medicine and related fields, as well as experts in imaging sciences and physics from all levels, ranging from students to advanced users and international experts. It is a symposium from the community for the community.

The scientific program comprises 13 sessions, covering a wide spectrum of renal physiology and pathologies, invasive quantitative approaches, optical imaging techniques, photoacoustic imaging and MR imaging. We are honored to present an array of outstanding international speakers including first class basic scientists, technology leaders and distinguished clinical experts. Focused sessions will provide deeper explanations into the most pressing imaging needs from the clinical perspective, and highlight the potential of renal imaging for the assessment of renal physiology, and the challenges en route to broader clinical applications.

Industry experts will present the current capabilities of functional MRI of the kidney, and outline the emergence of future renal MR imaging techniques. We aim to bridge disciplinary boundaries, and to engage the creativity and drive of the renal imaging community to solve the remaining challenges and overcome the barriers standing in the way of addressing unmet clinical objectives with renal functional imaging.

Poster sessions will run in parallel with the scientific program. We will also include multiple timeslots for poster power presentations, in order to bring to the attention of the audience a large number of poster presenters. Contributions of posters are strongly encouraged, and the best posters and poster power presentations, as judged by the audience, will receive an award.

We warmly invite you to join us for the 2nd International Symposium on Functional Renal Imaging in Berlin. Please save the date. A visit to Berlin is always worth it. Alongside the dynamic scientific landscape, Berlin has numerous historical landmarks, cultural highlights and sport events to offer.

We eagerly look forward to your participation. Be there – be Berlin!

Previous meeting: 1st international meeting on renal MRI
Next meeting: 3rd international meeting on renal MRI

Abstracts and registration

Every registered participant is invited to submit one or several abstracts for poster presentations. Abstracts may be composed of a text with a maximum length of 650 words and up to 3 figures. The deadline for abstract submission is 27 August, 2017.

The abstract submission deadline has been extended until 4 September, 10:00 a.m. (Central European Summer Time).

At the symposium a board will be assigned to each poster presenter to display their poster. The poster should have A0 size in portrait format (poster display dimension 100 cm wide x 120 cm high).

During the symposium there will be several Power Poster sessions that will give a large number of poster presenters the opportunity to showcase their work in a 3-minute oral presentation. We are looking forward to your poster contributions, which will be all considered for the symposium’s poster price contest.

Please be aware that you have to register for the symposium before you will be able to submit an abstract.

If you have any questions, please directly contact us: renalsymp@mdc-berlin.de.

Program

Scientific Program

Day 1

Wednesday 11 October 2017

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Introduction

10:30	Welcome & objectives of meeting
10:40	The PARENCHIMA initiative: Aims and roadmap Steven Sourbron – University of Leeds, UK

Renal Physiology

10:55	Renal physiology: Urine formation and salt-water balance Pontus Persson – Charité, Berlin, Germany
11:15	Renal physiology: Renal oxygenation Hans Joachim Schurek – Hannover Medical School, Germany
11:35	Renal physiology: Regulation of intrarenal oxygenation Roger Evans – Monash University, Melbourne, Australia
11:55	Renal physiology: Regulation of renal perfusion Erdmann Seeliger – Charité, Berlin, Germany

12:15

Light lunch (posters)

Renal Diseases & Pathophysiology - Part I

13:00	Nephrological perspectives: Acute kidney injury (AKI) Nicholas Selby – University of Nottingham, UK
13:20	Nephrological perspectives: Diabetic nephropathy Loreto Gesualdo – University of Bari, Italy
13:40	Nephrological perspectives: Chronic kidney disease (CKD) Alberto Ortiz – Autonomous University of Madrid, Spain
14:00	The link between Cardiac and renal diseases Ags Odudu – University of Manchester, UK
14:20	Modelling renal pathophysiology: Promises and challenges of animal models Andrea Fekete – Semmelweis University and Hungarian Academy of Sciences, Budapest, Hungary

Renal MR Imaging Methods

14:40	Fibrosis and microstructure: T1 relaxation, apparent diffusion, diffusion tensor imaging Neil Peter Jerome – Norwegian University of Science and Technology, Trondheim, Norway
15:00	*Oxygenation and blood volume: T2/T2 relaxation, BOLD, iron oxide enhancement** Andreas Pohlmann – Max Delbrück Center for Molecular Medicine, Berlin, Germany
15:20	Perfusion and filtration: arterial spin labeling, dynamic contrast enhancement Fabio Nery – UCL Great Ormond Street Institute of Child Health, London, UK
15:40	Molecular imaging: Hyperpolarisation, magnetization transfer, CEST Christoffer Laustsen – Aarhus University, Denmark

16:00

Coffee break (posters)

(Minimally) Invasive Quantitative Measurements

16:30	The physiologists tool kit: Quantitative invasive probes Kathleen Cantow – Charité, Berlin, Germany
16:50	Renal optical methods: Near infrared spectroscopy Dirk Grosenick – German Metrology Institute, Berlin, Germany
17:10	Renal optical methods: Hyperspectral imaging Wenke Markgraf – Dresden University of Technology, Dresden, Germany
17:30	Renal optical methods: Phosphorimetric pO2 measurement Philippe Guerci – University of Amsterdam, The Netherlands
17:50	Renal optical methods: Optoacoustic renal imaging Tim Devling – iThera Medical GmbH, Munich, Germany

18:30

Management committee meeting of the COST action PARENCHIMA
Steven Sourbron – University of Leeds, UK

Day 2

Thursday 12 October 2017

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Insights Into Dynamic Contrast-Enhanced MRI

09:00	What DCE MRI can(not) tell us about renal pathophysiology Arvid Lundervold – University of Bergen, Norway
09:20	Current challenges for using renal DCE MRI in the clinic Nicolas Grenier – University of Bordeaux, France

Insights Into Arterial Spin Labelling MRI

09:40

What ASL MRI can(not) tell us about renal pathophysiology
Charlotte Buchanan – University of Nottingham, UK

10:00

Current challenges for using renal ASL MRI in the clinic

María Fernández Seara – Universidad de Navarra, Pamplona, Spain

10:20

Coffee break (posters)

Renal Diseases & Pathophysiology - Part II

11:00	A pharmaceutical industry’s perspective on how renal imaging can enrich clinical trials Frank Czerwiec – Otsuka Pharmaceutical Development & Commercialization Inc., Washington D.C., USA
11:20	What does the nephrologist expect from functional renal imaging Kai-Uwe Eckardt – Charité, Berlin, Germany
11:40	What does the pathophysiologist expect from functional renal imaging Clive May – University of Melbourne, Australia
12:00	What does the radiologist expect from functional renal imaging Iosif Mendichovszky, Cambridge University Hospitals, UK
12:20	What does an expert radiographer expect from renal imaging Eli Eikefjord – University of Bergen, Norway

12:40

Lunch break (posters)

Insights Into Oxygenation MR Imaging

14:10	What oxygen sensitive MRI can(not) tell us about renal pathophysiology Pottumarthi Vara Prasad – NorthShore University HealthSystem, Evanston, USA
14:30	Current challenges for using renal BOLD MRI in the clinic Lilach Lerman – Mayo Clinic, Rochester, USA

Renal Power 1 - Clinical Research

(13 presentations of 3 min each)

14:50	Acute pyelonephritis in children: Diagnostics and comparison of two methods – static renal scintigraphy and MR imaging Alice Bosáková – University Hospital Ostrava-Poruba, Czech Republic
	Role of image and clinical-based biomarkers in renal transplant assessment Mohamed Abou El-Ghar – Urology & Nephrology Center, Mansoura University, Egypt
	The effect of enhancing spatial resolution in non-contrast enhanced renal MR angiography Anne Dorte Blankholm – Aarhus University Hospital, Denmark
	Reference method for measurement of total renal function - estimated versus measured GFR Martin Šámal – First Faculty of Medicine, Charles University & General University Hospital, Prague, Czech Republic
	The cortico-medullary ADC difference reduces inter-system variability in renal diffusion-weighted imaging Iris Friedli – Geneva University Hospitals, University of Geneva, Faculty of Medicine, Switzerland
	Feasibility study of diffusion tensor imaging of the kidneys in freely breathing infants with pyelonephritis Yvonne Simrén – Institute of Clinical Sciences at Sahlgrenska Academy, University of Gothenburg, Sweden
	Validation of single-kidney glomerular filtration rate measurement with dynamic contrast-enhanced MRI Susmita Basak – Division of Biomedical Imaging, LICAMM, University of Leeds, UK
	Repeatibility of renal BOLD MRI Anneloes de Boer – University Medical Center Utrecht, The Netherlands
	Feasibility of renal ASL in a pediatric cohort with impaired renal function Fabio Nery – UCL Great Ormond Street Institute of Child Health, London, UK
	Kidney fibrosis assessment: T1rho and DCE permeability study Dmitry Kupriyanov – Philips Healthcare, Moscow, Russia
	A pilot, multi-vendor comparison of multi-echo gradient-echo acquisitions for BOLD imaging in the kidney Pim Pullens – University Hospital Brussels, Belgium
	Diffusion weighted MR imaging to investigate response to therapy: A case report Anna Caroli – IRCCS - Istituto di Ricerche Farmacologiche Mario Negri, Bergamo, Italy
	Variability reduction in renal diffusion-weighted MR imaging with motion compensation Iris Friedli – Geneva University Hospitals, University of Geneva, Switzerland

Renal Power 2 - Experimental Research

(7 presentations of 3 min each)

15:35	The renal effect of anesthesia on the functional and metabolic phenotype in rats Haiyun Qi – MR Research Centre, Department of Clinical Medicine, Aarhus University, Denmark
	Simultaneous assessment of kidney perfusion and pH in an acute kidney injury murine model exploiting a dynamic CEST-MRI approach Dario Longo – National Research Council of Italy, Rome, Italy
	Assessment of metabolism in early renal ischemia/reperfusion injury using hyperpolarized 13C-pyruvate Per Mose Nielsen – Department of Clinical Medicine - Biomedical Radio Isotope Techniques, Aarhus, Denmark
	Measuring renal oxygenation in a mouse model of volume-dependent hypertension using BOLD MRI Dexter Lee – Howard University, Washington D.C., USA
	Quadrature birdcage RF coil for renal sodium (23Na) imaging in rodents at 9.4 T: Initial results Laura Böhmert – Max Delbrück Center for Molecular Medicine, Berlin, Germany
	Noninvasive evaluation of renal pH homeostasis after ischemia reperfusion injury by CEST-MRI pH mapping Dario Longo – National Research Council of Italy, Rome, Italy
	Diffusion-weighted split-echo RARE imaging free of geometric distortion for renal MRI at ultrahigh fields João dos Santos Periquito – Max Delbrück Center for Molecular Medicine, Berlin, Germany

16:00

Poster session (coffee break)

Insights Into Diffusion MR Imaging

16:50	What diffusion MRI can(not) tell us about renal pathophysiology Jean-Paul Vallee – University of Geneva, Switzerland
17:10	Current challenges for using renal diffusion MRI in the clinic Alexandra Ljimani – University of Düsseldorf, Germany

Social Event

19:00

Social Event

Day 3

Friday 13 October 2017

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Insights Into Emerging MR Technologies

09:00	Susceptibility MR: Better and bolder than BOLD Chunlei Liu – University of California, Berkeley, USA
09:20	Sodium MR is worth its salt! Stefan Zbyn – University of Oulu, Finland

Renal Power 3 - Multiparametric Studies

(9 presentations of 3 min each)

09:40	Assessment of renal stiffness in IgA nephropathy using multifrequency MRE compared to DWI and BOLD Stephan Marticorena Garcia – Charité - Universitätsmedizin Berlin, Germany
	Multiparametric kidney MR imaging to identify novel markers of disease progression in autosomal dominant polycystic kidney disease Albert Ong – University of Sheffield, UK
	Molecular DCE MRI with high and low temporal resolution, using bimodal AGulX contrast agents and multiparametric MRI in a murine UUO model Gregory Ramniceanu – Chimie ParisTech, Unité de Technologies Chimiques et Biologiques pour la Santé, France
	Multiparametric MRI of renal transplant: Preliminary comparison of advanced MRI parameters in patients with functional and fibrotic renal allografts Octavia Bane – Icahn School of Medicine at Mount Sinai Hospital, New York, USA
	MR imaging to assess the pathophysiology of acute kidney injury Huda Mahmoud – University of Nottingham, UK
	Hyperpolarized [13C,15N2]urea: A novel renal O2 saturation biomarker in acute kidney injury? Christian Mariager – Department of Clinical Medicine - Biomedical Radio Isotope Techniques, Aarhus, Denmark
	Non invasive MRI of renal physiology Per Eckerbom – Institute for Surgical Sciences, Uppsala University, Sweden
	Multiparametric assessment of chronic kidney disease Charlotte Buchanan – University of Nottingham, UK
	Evaluation of fibrosis models using 1H T1 mapping and slow component T2 23Na Per Mose Nielsen – Department of Clinical Medicine - Biomedical Radio Isotope Techniques, Aarhus, Denmark

Renal Power 4 - Segmentation & Modelling

(5 presentations of 3 min each)

10:10	Novel strategy for contrast-free MR angiography of arteriovenous fistulae for hemodialysis Andrea Remuzzi – University of Bergamo, Bergamo Italy
	*Semi-automated kidney delineation on BOLD images using k-means clustering of R2 signal decay** Anneloes de Boer – University Medical Center Utrecht, The Netherlands
	Fully automatic kidney segmentation in abdominal MR imaging using random forests (RFs) Marc Fischer – University of Tübingen, Germany
	The influence of hydration status of kidney volume and cyst measurements Jens Dam Jensen – Department of Clinical Medicine - Biomedical Radio Isotope Techniques, Aarhus, Denmark
	Fast semi-supervised segmentation of the kidneys in DCE-MRI using convolutional neural networks and transfer learning Alexander Lundervold – Western Norway University of Applied Sciences, Bergen, Norway

10:30

Poster session (coffee break)

The Industry's Perspective

11:10	Renal imaging in pharmaceutical research: Investigating glomerular pathophysiology using micro-CT Luke Xie – Genentech, San Francisco, USA
11:30	State-of-the-art and future directions in preclinical abdominal MRI Claudia Oerther – Bruker Biospin GmbH, Ettlingen, Germany
11:50	Clinical MRI of the kidneys – Today and tomorrow Hans Peeters – Philips Healthcare, Eindhoven, The Netherlands

Looking Beyond The Horizon

12:10	Improving diagnostic accuracy and treatment of renal diseases with computational models Anna Caroli – IRCCS - Istituto di Ricerche Farmacologiche Mario Negri, Ranica - Bergamo, Italy
12:30	Predictive analytics and machine learning for advancing renal diagnostics and therapies Kolja Bailly – Solandeo GmbH, Berlin, Germany
12:50	Practical challenges of multi-center studies and clinical renal imaging trials Paul Hockings – Antaros Medical, Gothenburg, Sweden

13:10	Adjourn (symposium)
13:20	Lunch break

Working Group Meetings organized by COST action PARENCHIMA
Plenary session

14:00	Introduction: Organization of the WG meeting Steven Sourbron – University of Leeds, UK
14:05	Working Group 1 pitch: objectives, progress, task forces, questions Reproducibility and standardization Christoffer Laustsen – Aarhus University, Denmark
14:20	Working Group 2 pitch: objectives, progress, task forces, questions Research and development toolbox (open-access toolbox with software & data) Frank G. Zöllner – Heidelberg University, Germany
14:35	Working Group 3 pitch: objectives, progress, task forces, questions Multi-centre clinical trial Anna Caroli – IRCCS – Istituto di Ricerche Farmacologiche Mario Negri, Ranica – Bergamo, Italy
14:50	Working Group 4 pitch: objectives, progress, task forces, questions Training programs Thoralf Niendorf – Max Delbrück Center for Molecular Medicine, Berlin, Germany
15:05	Working Group 5 pitch: objectives, progress, task forces, questions Dissemination (incl. PARENCHIMA Action website, intl. meetings) Marcos Wolf – Center for Medical Physics and Biomedical Engineering, Vienna, Austria

Working Group Meetings organized by COST action PARENCHIMA
Breakout sessions

15:30	Working Group 1: Improving the reproducibility and standardization of renal MRI Lead: Christoffer Laustsen, Aarhus University, Denmark
15:30	Working Group 2: Development of a renal MRI open-access toolbox with software & data Lead: Frank Zöllner, Heidelberg University, Germany
15:30	Working Group 3: Multi-centre clinical trial Lead: Anna Caroli, IRCCS – Istituto di Ricerche Farmacologiche Mario Negri, Ranica – Bergamo, Italy
15:30	Working Group 4: Development of a training program on renal MRI for basic scientists and clinical users Lead: Thoralf Niendorf, Max Delbrück Center for Molecular Medicine, Berlin, Germany
16:30	Reporting: Roles, planning, milestones, STSMs
17:15	Internal sum up per Working Group (task forces present their report; reports will be collated into a summary for newsletter/website)
17:30	Adjourn

Renal MRI Program 2017: Program and abstracts (PDF, 8.73 MB)

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Fees

Regular fee

Early (until 28.07.17): 300 €
Late (until 29.09.17): 400 €
On-site: 450 €

Student fee (incl. PhD students)

Early (until 28.07.17): 150 €
Late (until 29.09.17): 190 €
On-site: 200 €

Day ticket

Per day: 200 €

Organizers

Andreas Pohlmann (MDC)
Erdmann Seeliger (Charité)
Dirk Grosenick (PTB)
Sonia Waiczies (MDC)
Kathleen Cantow (Charité)
Pontus Persson (Charité)
Thoralf Niendorf (MDC)

Co-organizers

This symposium is co-organized by the European Cooperation in Science and Technology (COST) action 'MRI Biomarkers for Chronic Kidney Disease' (PARENCHIMA, CA16103).

Contact

Rosita Knispel
phone: +49 30 9406 4505

Lien-Georgina Dettmann
phone: +49 30 9406 2719

RenalSymp@mdc-berlin.de

Venue

Time

Catering

Program